FIELD: pharmacology.
SUBSTANCE: invention relates to unified assay of total flavonoids in three kinds of eyebright grass: Euphrasia brevipila Burnat@Gremli, Euphrasia parviflora Schag, and Euphrasia X reuteri Wettst, as well as in extractive preparations of Euphrasia brevipila Burnat@Gremli. Claimed method includes utilization of 2 % aluminum chloride alcohol solution as chelating agent and 8 % sodium acetate alcohol solution as ionizing agent; detection of colored complex by differential spectrophotometry at λ = 382±2 nm; and calculation of total flavonoids using specific absorption coefficient 
for cinarozide as reference standard and individual dilution series for each extractive preparation.
EFFECT: method for standardization of drug raw materials and eyebright extractive preparations according to active ingredient (flavonoid) content, useful in development of normative and technical documentation.
6 cl, 8 tbl, 6 ex, 1 dwg
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