METHOD FOR TREATING MITOCHONDRIAL DISORDERS Russian patent published in 2006 - IPC A61K31/7064 A61K31/70 A61P25/00 

FIELD: medicine.

SUBSTANCE: the present innovation deals with treating disorders chosen out of the group consisting of mitochondrial encephalomyopathy along with lactic academia and shock-like attacks (MELAS), neurogenic muscular fatigue, ataxia, retenitis pigmentosa/maternally inherited Li syndrome (NARP/MILS), syndrome of mitochondrial ataxia, relapsing infections, aphasia, hypouricemia/hypomyelination, attacks and aciduria of dicarbonic acids (MARIAHS), renal canalicular acidosis, Li syndrome, refractory epilepsy with deteriorations during infection, syndrome of multiple deletions mitochondrial DNA (mtDNA) and deficiency of cytochrome c-oxidase (COX, complex IV). Moreover, one should introduce efficient quantity of 2',3',5'-tri-O-acetyl-1-beta-D-uridine (triacetyluridine) for a patients who has such a disorder or with the risk for appearance of such a disorder. The innovation enables to either decrease or remove the symptoms of the diseases mentioned due to correcting the processes in synthetic pathway of pyrimidine.

EFFECT: higher efficiency of therapy.

19 cl, 5 ex, 1 tbl