METHOD FOR OBTAINING BETULONIC ACID Russian patent published in 2008 - IPC C07J53/00 C07J63/00 

Abstract RU 2333916 C1

FIELD: chemistry.

SUBSTANCE: invention relates to improved method for obtaining biologically active substances from products of chemical procession of birch bark outer layer, namely, to method for obtaining betulonic acid from betulin. Method lies in oxidation of betulin with Jones reagent in acetone at 0°C with mole ratio of betulin and chrome anhydrate equal to 1:6-1:7 during 20-30 minutes with further isolation of target product. The method allows simplification of obtaining betulonic acid due to reduction of betulin oxidation time from 7 to 0.5 hour and increase in its yield from 47 to 55.0%.

EFFECT: simplification of obtaining betulonic acid at an increase in its yield.

1 cl, 2 ex

Similar patents RU2333916C1

Title Year Author Number
METHOD FOR PRODUCING BETULONIC ACID 2015
  • Levdanskij Vladimir Aleksandrovich
  • Levdanskij Aleksandr Vladimirovich
  • Kuznetsov Boris Nikolaevich
RU2580106C1
METHOD FOR PREPARING BETULINIC ACID 2004
  • Levdanskij Vladimir Aleksandrovich
  • Polezhaeva Natal'Ja Ivanovna
  • Kuznetsov Boris Nikolaevich
RU2269541C1
METHOD FOR PREPARING BETULINIC ACID 2003
  • Kogaj T.I.
  • Levdanskij V.A.
  • Kuznetsov B.N.
RU2246500C1
METHOD FOR PRODUCING BETULONIC ACID 2014
  • Popov Sergej Aleksandrovich
  • Kozlova Ljubov' Pavlovna
  • Kornaukhova Ljubov' Mikhajlovna
  • Shpatov Aleksandr Vladimirovich
RU2568881C1
METHOD OF SYNTHESIS OF BETULINIC ACID 2001
  • Roshchin V.I.
  • Shabanova N.Ju.
  • Vedernikov D.N.
RU2190622C1
METHOD OF OBTAINING BETULINIC ACID 2011
  • Mel'Nikova Nina Borisovna
  • Ushkova Tat'Jana Mikhajlovna
  • Kislitsin Aleksej Nikolaevich
  • Klabukova Irina Nikolaevna
RU2463041C1
METHOD FOR PRODUCING BETULINIC ACID 2011
  • Mel'Nikova Nina Borisovna
  • Ushakova Tat'Jana Mikhajlovna
  • Kislitsin Aleksej Nikolaevich
  • Klabukova Irina Nikolaevna
RU2458933C1
METHOD FOR OBTAINING BETULINIC ACID 2010
  • Mel'Nikova Nina Borisovna
  • Burlova Irina Viktorovna
  • Kislitsin Aleksej Nikolaevich
  • Klabukova Irina Nikolaevna
RU2428426C1
ALLOBETULIN 3-O-BENZOATE SYNTHESIS METHOD 2008
  • Levdanskij Vladimir Aleksandrovich
  • Levdanskij Aleksandr Vladimirovich
  • Kuznetsov Boris Nikolaevich
RU2397989C1
N'-{N-[3-OXO-LUPAN-28-OYL]-9-AMINONONANOYL}-3-AMINO-3-PHENYLPROPIONIC ACID AND ITS SALTS AS ANTIVIRAL AND IMMUNOSTIMULATING AGENTS 2006
  • Dzhemilev Usein Memetovich
  • Tolstikov Genrikh Aleksandrovich
  • Pokrovskij Andrej Georgievich
  • Salakhutdinov Nariman Faradovich
  • Tolstikova Tat'Jana Genrikhovna
  • Shul'Ts Ehl'Vira Ehduardovna
RU2317996C1

RU 2 333 916 C1

Authors

Kogaj Tamara Ivanovna

Kuznetsov Boris Nikolaevich

Dates

2008-09-20Published

2007-03-12Filed