METHOD FOR PRODUCING BETULONIC ACID Russian patent published in 2015 - IPC A61K36/185 A61K31/15 B01D11/02 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pharmaceutical industry, namely to a method for producing betulonic acid. The method for producing betulonic acid consisting in the fact that birch bark is extracted in methyl tertiary butyl ether to producing an extract containing 3.9-12 wt % of extractive substances; the produced extract is oxidised with Jones's reagent; the reaction mixture is treated with HCl solution; the separated organic solution is treated with NaOH solution; deposited sodium salt of betulonic acid is filtered; betulonic acid is filtered; the filtrate is concentrated and dissolved in ethanol, filtered; the filtrate is concentrated and oxidised with HCl solution, dried to recover an end product in the certain environment.

EFFECT: method described above is characterised by simplicity, cost effectiveness, absence of environment contamination with organic substances, and small amount of water waste.

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