FIELD: medicine.
SUBSTANCE: method involves para-articularly introducing adrenaline to rat ill in age-specific osteoporosis and renal osteodystrophy every day. 0.2 ml of 0.1% adrenalin solution is introduced during 6 weeks and 0.12 mg of methyl prednisolone is intra-articularly introduced twice a week under patella.
EFFECT: high reproducibility of focal bone necrosis model.
6 dwg, 1 tbl
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