FIELD: medicine.
SUBSTANCE: invention relates to Legg-Calve-Perthes disease (LCPD) model, which can be used to test various treatments and osteonecrosis prevention agents. The simulation method involves introduction of 0.1% epinephrine in the periarticular tissues of the hip joint at a dose of 0.5 ml daily for 1 month. From the 15th day of preparation administration, tractions are applied additionally to the hip joint, including full flexion with limb subsequent extension, daily, 10 times of 3 repetitions, for 15 days.
EFFECT: method increases the simulation reliability due to the effect on different parts of disease pathogenesis with decreased invasiveness and risk of animals death.
1 ex, 4 dwg
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