APPARATUS FOR SUSPENSION CULTIVATION OF TISSUE AND MICROORGANISM CELLS Russian patent published in 2006 - IPC C12M1/04 C12M3/00 

FIELD: biotechnology.

SUBSTANCE: claimed apparatus contains fermentation vessel with closure and nipples for aerating gas feeding and gaseous medium discharge, respectively; and devise for cultural medium aeration and agitation. Said devise contains aerating gas circuit comprising pipeline and screen installed inside of vessel above outlet port of pipeline. Screen is placed horizontally and with gap to vessel walls to form gas cushion under thereof. Device also contains attachment for forming gas cushion vibration to agitate the cultural medium and gas flow controller, interconnected with abovementioned pipeline. Apparatus may be equipped by one or more said devices for cultural medium aeration and agitation. Screen has quarrel cross-section having longitudinal slit in bottom part for reciprocal movement of cultural medium flow. Attachment for forming gas cushion vibration contains pulsator with mobile membrane to produce reciprocal movement of gas flow in gas cushion under screen.

EFFECT: increased mass exchange effectiveness in cell cultivation process due to enhanced gas-liquid boundary surface; apparatus of increased productivity.

4 cl, 4 dwg