METHOD FOR PRODUCTION OF LATEX DIAGNOSTICUM FOR LATEX-AGGLUTINATION REACTION Russian patent published in 2006 - IPC G01N33/531 

FIELD: veterinary virology, in particular production of latex diagnosticum for diagnosis of horned cattle and poultry infections.

SUBSTANCE: claimed method includes centrifugation of polymeric suspension and adjusting of polymeric suspension with distilled water up to 0.5 % (calculated as polymer dry residue)/ Then equal volumes of viral antigen in infective titer of 6.5 lg TCD/₅₀ ml (tissue cytopatic doses) and 0.5 %-1.0 % polymeric suspension are mixed and mixture is hold in thermostatic regulator at 36-38°C for 4-6 h. Further 0.07-0.15 % aqueous solution of human serum albumin is added into total suspension volume, mixture is incubated .at 4-8°C for 11-13 h; suspension is washed, and diagnosticum concentration is adjusted with phosphate buffered saline with pH 7.2-7.4 up to 0.1-0.3 %. Prepared diagnosticum is stored at 4°C not more than 1 year.

EFFECT: diagnosticum for before-the-fact detection of different infective diseases, prophylaxis and treatment.

7 ex, 7 tbl