PEPTIDES OF DIRECTED ACTION OF VEGFR-1/NRP-1 Russian patent published in 2013 - IPC C07K5/83 C07K7/06 A61K38/06 A61K38/08 A61K47/48 

Abstract RU 2488592 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to molecular medicine and a target-directed drug delivery. There are presented new peptide sequences sized 10 or less amino acids containing at least a continuous amino acid sequence D(LPR) which selectively influence on the VEGFR-1 and NRP-1 expressing cells.

EFFECT: target-directed molecules according to the inventions are applicable for treating and diagnosing the neovascular and angiogenic VEGF-associated disorders, such as cancer, obesity, diabetes, asthma, arthritis, cirrhosis and eye diseases.

16 cl, 4 dwg, 2 ex

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RU 2 488 592 C2

Authors

Paskualini Renata

Arap Vadikh

Zhiurdanu Rikardu

Kardo-Vila Marina

Valente Ana Paula

Seneviva Laserda De Al'Mejda Fabiu

Dates

2013-07-27Published

2008-08-08Filed