FIELD: medicine.
SUBSTANCE: formula bond 
or it pharmaceutically comprehensible salt where value of radicals are specified in the invention formula is described. The bonds are effective as inhibitors of protein kinases FLT-3 or KIT. A way of inhibition of activity kinases FLT-3 or KIT in the biological sample in vitro and application of bonds for manufacture of a medical product, suitable for treatment or simplification of gravity of disease or a condition, the chosen acute myelogenetic leukosis, acute progranulocytic leukemia or acute lymphocytic leukosis or cancer of ovaries are described also.
EFFECT: rising of efficiency of a composition and the method of treatment.
11 cl, 86 ex
| Title | Year | Author | Number |
|---|---|---|---|
| 7-SUBSTITUTED INDOLE Mcl-1 INHIBITORS | 2008 |
|
RU2473542C2 |
| DERIVATIVES OF SUBSTITUTED TRIAZOLDIAMINE, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD FOR ITS PREPARING | 2001 |
|
RU2274639C2 |
| AMINOTRIAZOLOPYRIDINES AND USING THEM AS KINASE INHIBITORS | 2009 |
|
RU2552642C2 |
| DERIVATIVES OF DIAMINES | 2002 |
|
RU2319699C2 |
| DIAMINE DERIVATIVES | 2002 |
|
RU2314303C2 |
| HETEROARYL COMPOUNDS, COMPOSITIONS CONTAINING THEM AND METHODS OF TREATING WITH USE OF SUCH COMPOUNDS | 2007 |
|
RU2478635C2 |
| 1,2,4-TRIAZOLONE DERIVATIVE | 2011 |
|
RU2566754C2 |
| BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR TREATING CANER AND IMMUNE DISEASES | 2010 |
|
RU2542994C2 |
| PYRIMIDINE DERIVATIVES | 2002 |
|
RU2320658C2 |
| CONDENSED PYRIDAZINE DERIVATIVES AND DRUGS HAVING THE COMPOUNDS AS ACTIVE INGREDIENTS | 2003 |
|
RU2292337C2 |
