Show metadata Hide metadata

(19)

(11)

2 758 686

(13)

(51)

IPC

C07D215/12(2006-01-01)

C07D215/14(2006-01-01)

C07D215/18(2006-01-01)

C07D241/42(2006-01-01)

C07D401/04(2006-01-01)

C07D401/12(2006-01-01)

C07D401/14(2006-01-01)

C07D413/04(2006-01-01)

C07D413/14(2006-01-01)

C07D451/02(2006-01-01)

C07D471/04(2006-01-01)

C07D471/08(2006-01-01)

C07D471/10(2006-01-01)

C07D487/04(2006-01-01)

C07D487/08(2006-01-01)

A61K31/4375(2006-01-01)

A61K31/4709(2006-01-01)

A61K31/498(2006-01-01)

A61K31/4545(2006-01-01)

A61K31/496(2006-01-01)

A61K31/4995(2006-01-01)

A61K31/5377(2006-01-01)

A61P1/04(2006-01-01)

A61P13/12(2006-01-01)

A61P17/00(2006-01-01)

A61P17/06(2006-01-01)

A61P19/02(2006-01-01)

A61P19/06(2006-01-01)

A61P19/08(2006-01-01)

A61P19/10(2006-01-01)

A61P25/00(2006-01-01)

A61P25/16(2006-01-01)

A61P25/28(2006-01-01)

A61P29/00(2006-01-01)

A61P29/02(2006-01-01)

A61P3/10(2006-01-01)

A61P35/00(2006-01-01)

A61P9/10(2006-01-01)

(21) (22)

Application

2019105719, 2017-08-07

(24)

Start date

2017-08-07

(22)

Actual filing date

2017-08-07

(45)

Published

2021-11-01

(72)

Inventor

Sherer Brajan A.Chen SyaolinKliri EsterBrugger Nadiya

(73)

Holder

Merck Patent Gmbh

TLR7/8 ANTAGONISTS AND THEIR APPLICATION Russian patent published in 2021 - IPC C07D215/12 C07D215/14 C07D215/18 C07D241/42 C07D401/04 C07D401/12 C07D401/14 C07D413/04 C07D413/14 C07D451/02 C07D471/04 C07D471/08 C07D471/10 C07D487/04 C07D487/08 A61K31/4375 A61K31/4709 A61K31/498 A61K31/4545 A61K31/496 A61K31/4995 A61K31/5377 A61P1/04 A61P13/12 A61P17/00 A61P17/06 A61P19/02 A61P19/06 A61P19/08 A61P19/10 A61P25/00 A61P25/16 A61P25/28 A61P29/00 A61P29/02 A61P3/10 A61P35/00 A61P9/10

Abstract RU 2758686 C2

FIELD: pharmaceutics.

SUBSTANCE: invention relates to compounds of the formula I, their pharmaceutically acceptable compositions suitable as TLR7/8 antagonists.

EFFECT: obtaining TLR7/8 antagonists.

10 cl, 33 ex, 1 tbl

Similar patents RU2758686C2

Title	Year	Author	Number
QUINOLINE-2 DERIVATIVES AS C-KIT KINASE INHIBITORS	2016	Dorsh Diter Myuzerell Matilda Burgdorf Lars Vukherer-Plitker Margarita Chodrovski Paul Esdar Kristina Tsaklakidis Khristos	RU2754858C2
ISOINDOLINE COMPOUND, PRODUCTION METHOD, PHARMACEUTICAL COMPOSITION AND THEIR USE	2019	Chen, Xiaohua Li, Jia Cheng, Yu Zhou, Yubo Nie, Huijun Wang, Yujie Tian, Hongtao Kan, Weijuan Mi, Tian Hu, Xiaobei Zhou, Binshan Yan, Kenian Xu, Gaoya Zhong, Yuhua Feng, Lei	RU2813232C2
4-(IMIDAZO[1,2-A]PYRIDIN-3-YL)-PYRIMIDINE DERIVATIVES	2020	Dorsch Dieter Blum Andreas Buchstaller Hans-Peter	RU2822388C2
BENZIMIDAZOLE DERIVATIVES EFFECTIVE IN TREATING RESPIRATORY SYNCYTIAL VIRUS INFECTION	2012		RU2612530C2
OXOQUINAZOLINYL-BUTANAMIDE DERIVATIVES	2014	Dorsh Diter Bukhshtaller Khans-Peter	RU2669393C2
PIPERIDINE UREA DERIVATIVES	2014	Bukhshtaller Khans-Peter Dorsh Diter	RU2666894C2
CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DESTRUCTION OF ANDROGEN RECEPTORS AND USE THEREOF	2020	Du, Vu Ven, Kun Fu, Ivej Lv, Khajbin Khe, Tszinyun Tsin, Dekun Li, Yuj Duan, Tszini Li, Yun Aj, Chaovu Tu, Chzhilin Chen, Yuanvej Li, Sinkhaj Li, Khajbo	RU2825000C2
3-AMINOCYCLOPENTANCARBOXAMIDE DERIVATIVES	2013	Tsaklakidis Khristos Shtele Volfgang Lojtner Brigitta Chodrovski Paul	RU2641913C2
MACROCYCLIC PYRIDAZINONE DERIVATIVES	2014	Zhoran-Lebryun Katrin Kulkarni Santosh Kristmann-Frank Serzh	RU2660435C2
PYRAZOLE COMPOUNDS, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR APPLICATION	2019	Syue Chubyao Khuan Lie Li Khua Li Tao Lyu Khuabin	RU2770835C1

RU 2 758 686 C2

Authors

Sherer Brajan A.

Chen Syaolin

Kliri Ester

Brugger Nadiya

Dates

2021-11-01—Published

2017-08-07—Filed