FIELD: medicine, biotechnology.
SUBSTANCE: invention relates to preparing biologically active substances from human and animal tissues. Invention proposes an antibacterial agent from pig and cattle platelets of molecular mass 0.5-15 kDa. Agent is prepared by freezing and defrosting platelet mass at temperature (-15)-(-20)°C for 24 h, centrifugation at 1000g, filtration of supernatant through dialysis membranes 15000 and 500 and elution of component comprising peptides by acetonitrile linear gradient from Sephadex G-50. Invention provides the synergetic antibacterial effect of peptides as component of the agent.
EFFECT: improved preparing method, valuable properties of agent.
8 cl, 6 tbl, 7 ex
| Title | Year | Author | Number |
|---|---|---|---|
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|
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