NEW BIOPOLYMERS PRODUCED BY IRRADIATION IN THE SOLID PHASE IN THE ATMOSPHERE OF THE UNSATURATED GASES Russian patent published in 2006 - IPC C07K1/00 C08F2/46 C08H1/00 C08J3/28 

FIELD: chemical industry; biotechnology; production of the new biopolymers by irradiation in the solid phase.

SUBSTANCE: the invention is pertaining to the new products produced on the basis of the biopolymers. The method of modification of the existing in the nature biocompatible biopolymer, which is characterized by the lack of any functional groups, provides for the treatment of the indicated biopolymer being in the solid or the dry state with the source of the ionizing radiation at the presence of the mediating gas. The mediating gas represents the unsubstituted alkene or alkyne gas, in capacity of which may be ethylene, propylene or acetylene and the annealing of the obtained product in the absence of oxygen at the temperature from nearby 40°C up to 120°C, with the subsequent removal of the all remained mediating gas. The modified biopolymer is produced by the above-stated method. The present in the nature modified biocompatible biopolymer produced by the above-stated method is sampled from the group consisting of polysaccharides of the vegetable or animal origin and the protein produced from the connective tissue of an animal, the protein produced from the other tissues of an animal, the combinations of at least of one of the indicated polysaccharides and at least of one other protein of the vegetable origin, or the demineralized bone ("DMB"). The method of modification of the tissue of the animal origin includes switches the treatment of the sample of the indicated tissue or its component in the solid or the dry state with the source of the ionizing radiation at the presence of the mediating gas and the annealing of the obtained product in the absence of the oxygen at the temperature from around 40 up to 120°C, with the subsequent removal of the all remained mediating gas. The invention allows to obtain the biopolymers possessing the good biocompatibility. At that into the source biopolymer do not introduce neither new, nor additional functional groups.

EFFECT: the invention allows to obtain the biopolymers possessing the good biocompatibility.

35 cl, 6 ex, 12 tbl, 43 dwg