FIELD: biotechnology, microbiology.
SUBSTANCE: invention proposes the strain Lactobacillus fermentum ME-3 DSM 14241 isolated from feces of health one year-old Estonian baby. The strain elicits high antibacterial effect in strain Escherichia coli, Shigella sonnei, Staphylococcus aureus, Salmonella typhimurium 1 and 2 and moderate activity against strain Helicobacter pylori, and it elicits also activity of [Mn]-dependent superoxide dismutase. Both its lysates and intact cells show antioxidant activity, increases the ratio reduced glutathione to oxidized glutathione in serum blood and able to trap toxic hydroxyl radicals. The strain L. fermentum ME-3 DSM 14241 is used as a probiotic, in preparing functional foodstuffs (yogurt, cheese) and non-foodstuffs (tablets, capsules), for prophylaxis of intestine and urinary infections being both for prophylaxis and treatment of chronic diseases caused by the prolonged oxidative stress. The strain elicits high antibacterial effect that promotes to prevention of pathogens multiplication in foodstuffs fermented by this strain and prevents infections associated with feeding.
EFFECT: valuable properties of probiotic.
4 cl, 6 tbl, 1 ex
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