COMPOSITE PROBIOTIC PREPARATION AND METHOD FOR PREPARING IT Russian patent published in 2013 - IPC A61K35/74 A61K31/718 A61K31/7016 A61P1/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pharmaceutical industry, and represents a composite probiotic preparation containing probiotic lactic acid bacilli and bifidus bacteria cells, or mixtures thereof, and a polymer additive in an enterosoluble capsule, differing by the fact that the probiotic lactic acid bacilli and bifidus bacteria cells belong to the species Lactobacillus plantarum, Lactobacillus fermentum, Lactobacillus acidophilus, Lactobacillus casei, Bifidobacterium bifidum, Bifidobacterium longum, while the polymer additive used as a binding agent and being a polysaccharide, is specified in a group: amylopectin, waxy corn starch, native potato starch, soluble potato starch, wheat starch, maltodextrin, or mixtures thereof with the above ingredients of the composite preparation are taken in ratio 10⁸-10¹² probiotic lactic acid bacilli and bifidus bacteria cells per 0.01-1 g of the polymer additive.

EFFECT: invention provides creating more effective and stable probiotic preparation for preventing and treating intestinal dysbacterioses and intestinal infections, as well as increasing an ability of the preparation to produce nitrogen monoxide by NO-synthase mechanism.

2 cl, 1 ex, 1 tbl, 5 dwg