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2 285 008

(13)

(51)

IPC

C07D493/12(2006-01-01)

C12P17/18(2006-01-01)

C12N1/02(2006-01-01)

A61K31/352(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2003102446/04, 2001-06-29

(24)

Start date

2001-06-29

(22)

Actual filing date

2001-06-29

(45)

Published

2006-10-10

(72)

Inventor

Peres-Bas KhulijaKan'Edo Librada MarijaGarsia Gravalos DoloresRomero FransiskoEhspliego Fernando

(73)

Holder

Instituto Biomar S.A.

NOVEL POLYCYCLIC XANTHONES AND THEIR USING Russian patent published in 2006 - IPC C07D493/12 C12P17/18 C12N1/02 A61K31/352 A61P35/00

Abstract RU 2285008 C2

FIELD: organic chemistry, microbiology, medicine, oncology.

SUBSTANCE: invention relates to novel class of antitumor compounds found in isolation from new marine microorganisms of genus Actinomadura sp., strain PO13-046, namely, to compound denoted as IB-00208: and relates to class of compounds of the formula (I) or (II) , wherein each substitute R¹ is similar or different and can represent hydrogen atom, acyl, alkyl, alkenyl, aryl, benzyl, alkaline metal and/or monosaccharide, disaccharide, trisaccharide or their derivative; R² and R³ can represent hydrogen atom or alkyl. These compounds show antitumor activity.

EFFECT: valuable medicinal properties of compounds.

8 cl, 3 tbl, 9 dwg, 11 ex

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RU 2 285 008 C2

Authors

Peres-Bas Khulija

Kan'Edo Librada Marija

Garsia Gravalos Dolores

Romero Fransisko

Ehspliego Fernando

Dates

2006-10-10—Published

2001-06-29—Filed