FIELD: genetic engineering, biochemistry, pisciculture.
SUBSTANCE: invention relates to the determined nucleotide sequence encoding glycoprotein of the Russian isolate ZL-4. Based on this sequence DNA-plasmids are constructed that provide expression of glycoprotein of the Russian isolate ZL-4 in fishes. DNA-vaccine constructed on basis of indicated DNA-plasmids provides the development of protective immunity in fishes against the following infection with ZL-4 isolate of carp spring viremia virus. Using the invention provides protection of carp in Russian aquaculture from the following infection with carp spring viremia virus.
EFFECT: valuable properties plasmid DNA and glycoprotein gene.
3 cl, 4 dwg, 3 ex
| Title |
Year |
Author |
Number |
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|
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|
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|
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