RECOMBINANT PLASMID DNA p30NE2, ENCODING 181-AMINO ACID N-TERMINAL FRAGMENT OF GLYCOPROTEIN E2 OF CLASSICAL BOG CHOLERA VIRUS AND PROVIDING EXPRESSION THEREOF IN CELLS Russian patent published in 2005 - IPC

Abstract RU 2250263 C1

FIELD: genetic engineering.

SUBSTANCE: recombinant plasmid DNA p30NE2 contains DNA fragment of pasmid pQE30, including promoter/operator of T5 phage; ribosome-binding site; phage lambda transcription terminator, and β-lactomase gene as genetic marker, as well as BamHI/HindIII fragment, encoding 181-amino acid N-terminal fragment of glycoprotein E2 of classical bog cholera virus. Plasmid provides expression of glycoprotein E2 of classical bog cholera virus in E/coli bacteria cells. Invention is useful in diagnostic investigation and in vaccine production.

EFFECT: genetically engineered plasmid for vaccine preparations.

3 dwg, 6 ex

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RU 2 250 263 C1

Authors

Andreev V.G.

Bezborodova S.V.

Dates

2005-04-20Published

2003-08-05Filed