FIELD: organic chemistry, industrial microbiology, biochemistry.
SUBSTANCE: invention relates to a method for producing amide compound from a nitrile compound by using bacterial cells possessing nitrile hydratase activity. Bacterial cells are contacted with nitrile compound in an aqueous medium at continuous addition of a nitrile compound and without immobilization of cells by uptake that results to accumulation of amide compound in medium in the concentration 20% and above. Proposed invention provides enhancing the output of method in producing amide compound based on preparing the higher concentration of amide compound in medium and for shorter time period.
EFFECT: improved producing method.
6 cl, 4 ex
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