FIELD: medicine, endocrinology, pharmacy.
SUBSTANCE: invention relates to a pharmaceutical composition comprising epidermal growth factor (EGF) used in treatment of wounds on skin and soft tissues of lower limb in diabetic patient. Method of treatment involves topical infiltration of EGF-containing solution into different points and by contours of tissue damaged zone to provide administration of the solution into wound in the total volume 4-20 ml and irrigation of all deep surface of wound base and edges with the indicated composition. Invention provides prevention of diabetic limb amputation, stimulation of cellular proliferation in patients with foot ulcer being especially in geriatrics.
EFFECT: valuable medicinal properties of pharmaceutical composition.
19 cl, 1 tbl, 9 ex
| Title | Year | Author | Number |
|---|---|---|---|
| PHARMACEUTICAL COMPOSITION IN FORM OF MICROSPHERES FOR PREVENTION OF EXTREMITY AMPUTATION IN CASE OF DIABETES | 2007 |
|
RU2426528C2 |
| APPLICATION OF LOCAL COMPOSITION, CONTAINING EPIDERMAL GROWTH FACTOR (EGF), FOR PREVENTION OF AMPUTATION CAUSED BY DIABETIC FOOT | 2006 |
|
RU2394590C2 |
| VESICLES COMPRISING EPIDERMAL GROWTH FACTOR AND COMPOSITIONS THEREOF | 2013 |
|
RU2649781C2 |
| LIPID NANOPARTICLES FOR HEALING WOUNDS | 2014 |
|
RU2662097C2 |
| APPLICATION OF EPIDERMAL GROWTH FACTOR FOR MORPHOFUNCTIONAL RECOVERY OF PERIPHERAL NERVES IN DIABETIC NEUROPATHY | 2007 |
|
RU2460536C2 |
| METHOD FOR TREATING ULCEROUS DEFECTS AT DIABETIC FOOT SYNDROME | 2006 |
|
RU2322247C1 |
| METHOD FOR TREATMENT OF UNINFECTED POSTOPERATIVE WOUND DEFECT OF THE FOOT IN THE ABSENCE OF SIGNS OF CRITICAL LIMB ISCHEMIA IN PATIENTS WITH NEUROPATHIC AND NEUROISCHEMIC FORMS OF DIABETIC FOOT SYNDROME | 2020 |
|
RU2754383C1 |
| METHOD OF TREATING DIABETIC FOOT ULCERS, PRESSURE ULCERS, VENOUS LEG ULCERS AND ASSOCIATED COMPLICATIONS | 2013 |
|
RU2664710C2 |
| APPLICATION OF PHARMACEUTICAL COMPOSITIONS IN MANUFACTURING MEDICATIONS FOR TREATMENT OF DIABETIC ULCERS | 2010 |
|
RU2523889C2 |
| METHOD FOR TREATING DIABETIC FOOT SYNDROME BEFORE FORMATION OF ULCEROUS DEFECT USING EXTRACORPORAL SHOCK WAVE THERAPY | 2016 |
|
RU2632683C1 |
