FIELD: organic chemistry, steroids, chemical technology.
SUBSTANCE: invention describes a method for synthesis of 7-substituted steroid compounds of the general formula (I):
wherein R1 means hydrogen atom (H) or -COR2 group wherein R2 means (C1-C6)-alkyl, (C1-C6)-alkoxy-group; Z1 means -CH2- or 
wherein R3 is in α-configuration; R3 means H or -COR2; Z2 means -CH-, or Z1 and Z2 mean in common a double bond; Q means 
,
,
,
,
,
,
; Y means -CN, -CH2-CH=CH2 or -CHR4C(O)Ar, -CHR4C(O)-(C1-C6)-alkyl, -CHR4C(O)XAr or -CHR4C(O)X-(C1-C6)-alkyl wherein R4 means -O-(C1-C6)-alkyl or aryl X means oxygen (O) or sulfur (S) atom that are intermediate compounds used in synthesis of eplerenon.
EFFECT: improved method of synthesis.
7 cl, 1 tbl, 2 dwg, 20 ex
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