FIELD: medicine, namely, modeling, possible use for modeling destructive changes in rat lungs.
SUBSTANCE: in accordance to method, immunodeficiency state is created by means of injection of 2,5% solution of hydrocortisone acetate in amount of 35 mg/100g of body mass of rat thrice a day, and on 7th day culture Klebsiella pneumonia is introduced in dose of 1 million microbe bodies for 100g of body mass of rat by means of penetration of chest wall in 3-5 intercostal space along side surface.
EFFECT: creation of adequate lung destruction model.
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