METHOD FOR SIMULATING TYPHOID ON SMALL LABORATORY ANIMALS WITH ARTIFICIAL IMMUNOSUPPRESSION Russian patent published in 2020 - IPC G09B23/28 

Abstract RU 2716753 C1

FIELD: medicine.

SUBSTANCE: invention refers to experimental medicine and medical microbiology. Guinea pigs are injected abdominally with dexamethasone at dose of 0.8 mg/kg once daily for 3 days. Two days after the last injection, the animal is injected intratesticularly with an excitatory culture in a sublethal dose of 100 million live microbes.

EFFECT: method enables developing certain manifestations of an infectious process, the use of which is necessary to solve a number of practical problems associated with assessing the pathogenic properties of microbes, animating laboratory cultures, assessing the effectiveness of therapeutic agents and prevention.

1 cl, 6 tbl, 5 ex

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RU 2 716 753 C1

Authors

Okhapkina Veronika Yurevna

Pyatkova Nadezhda Vitalevna

Baramzina Galina Valerevna

Fomenkov Oleg Olegovich

Fedotov Andrej Konstantinovich

Baryshev Maksim Nikolaevich

Dates

2020-03-16Published

2019-03-26Filed