DERIVATIVES OF OLIGOSACCHARIDES Russian patent published in 2006 - IPC C07H15/203 C07H17/02 A61K31/7028 A61K31/7032 A61P3/06 A61P3/10 

Abstract RU 2290408 C2

FIELD: organic chemistry, sugars, medicine, pharmacy.

SUBSTANCE: invention relates to novel compounds of the formula (I): wherein A represents compounds of the general formula (A1) wherein R1 and R2 are similar or different and each represents (C1-C6)-alkyl group, hydroxymethyl group, (C1-C6)-alkoxymethyl group or (C1-C6)-halogenalkyl group; R3, R4, R5 and R6 can be similar or different and each represents (C1-C6)-hydroxyalkyl group, (C1-C6)-halogenalkyl group, amino-group wherein amino-group can be optionally substituted with one or two (C1-C6)-hydroxyalkyl groups, hydroxyl group, hydrogen atom or halogen atom; R7 represents hydrogen atom; n represents a whole number 1 or 2, and its pharmacologically acceptable salts or pharmacologically acceptable esters. Compounds elicit the excellent activity and stability and useful in treatment and/or prophylaxis of diabetes mellitus and other diseases. Also, invention relates to pharmaceutical compositions, inhibitor of α-amylase, hypoglycemic agent based on these compounds, and to a method for treatment or prophylaxis of diabetes mellitus and other diseases.

EFFECT: valuable medicinal properties of compounds and pharmaceutical composition.

20 cl, 8 tbl, 24 ex

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RU 2 290 408 C2

Authors

Khonda Takesi

Okuno Akira

Izumi Masanori

Li Sjaolju

Dates

2006-12-27Published

2004-01-29Filed