FIELD: organic chemistry, medicine, pharmacy.
SUBSTANCE: invention describes a method for synthesis of compound of the formula 
wherein B means lipid being cholesterol preferably; A means fragment with valuable properties; X means a linker. Synthesis involves interaction of compound of the formula (I): 
with compound of the formula (II): 
in mixture or bound with a nucleotide sequence, or with a pharmaceutically active agent; R1 means hydrogen atom (H), and R2 means unshared pair or H. Synthesized compounds are designated for treatment of the genetic injury of disease.
EFFECT: improved method of synthesis, valuable medicinal properties of compounds.
23 cl, 1 tbl, 6 dwg, 1 ex
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