METHOD FOR PREPARING 3-PHENYL-1,3,4-THIADIAZOLIDINE Russian patent published in 2007 - IPC C07D285/12 

Abstract RU 2291148 C1

FIELD: organic chemistry, organic synthesis, chemical technology.

SUBSTANCE: invention relates to the improved method for synthesis of 3-phenyl-1,3,4-thiadiazolidine of the general formula (1): Method involves interaction of formaldehyde aqueous solution saturated with hydrogen sulfide with phenylhydrazine hydrochloride in ethanol medium and taken in the mole ratio phenylhydrazine : formaldehyde solution : hydrogen sulfide = 1:2:1, respectively, at temperature 0°C and at stirring for 3 h. Substances synthesized by the proposed method can be used as selective sorbents and extractants of precious metals, special reagents for inhibition of vital activity of microorganisms in different media (from light industry to petroleum extracting industry), biologically active substances used in synthesis of different medicinal preparations, for example, anti-bacterial, anti-fungal and anti-viral agents. The yield of the end substance (1) is 21%.

EFFECT: improved method of synthesis.

1 ex

Similar patents RU2291148C1

Title Year Author Number
METHOD FOR COMBINED PREPARING 3,4-DIPHENYL-1,3,4-THIADIAZOLIDINE AND 5,6-DIPHENYLTETRAHYDRO-1,3,5,6-DITHIADIAZEPINE 2005
  • Akhmetova Vnira Rakhimovna
  • Nadyrgulova Guzel' Razhapovna
  • Khafizova Svetlana Rinatovna
  • Kunakova Rajkhana Valiullovna
  • Tjumkina Tat'Jana Viktorovna
  • Dzhemilev Usein Memetovich
RU2291149C1
METHOD FOR PREPARING DI-[(6-BENZYL-4,2,6-THIADIAZOLIDINE-2-YL)METHYL]SULFIDE 2006
  • Akhmetova Vnira Rakhimovna
  • Nadyrgulova Guzel' Razhapovna
  • Khafizova Svetlana Rinatovna
  • Kunakova Rajkhana Valiullovna
  • Tjumkina Tat'Jana Viktorovna
  • Dzhemilev Usein Memetovich
RU2305098C1
METHOD FOR PREPARING N-METHYLENE-4H-1,3,5-DITHIAZINYL-5(6H)-AMINE 2005
  • Dzhemilev Usein Memetovich
  • Akhmetova Vnira Rakhimovna
  • Nadyrgulova Guzel' Razhapovna
  • Khafizova Svetlana Rinatovna
  • Kunakova Rajkhana Valiullovna
  • Tjumkina Tat'Jana Viktorovna
RU2291864C1
METHOD FOR PREPARING N-PHENYL-1,3,5-DITHAZINE-5-AMINE 2005
  • Akhmetova Vnira Rakhimovna
  • Nadyrgulova Guzel' Razhapovna
  • Khafizova Svetlana Rinatovna
  • Kunakova Rajkhana Valiullovna
  • Tjumkina Tat'Jana Viktorovna
  • Dzhemilev Usein Memetovich
RU2291151C1
METHOD OF PRODUCING N-PHENYL(BENZYL)-1,5,3-DITHIAZEPINANE-3-AMINES AND 2,4-DIMETHYL-N-PHENYL(BENZYL)-1,5,3-DITHIAZEPINANE-3-AMINES 2010
  • Dzhemilev Usein Memetovich
  • Murzakova Natalija Nail'Evna
  • Khabibullina Guzel' Razhapovna
  • Akhmetova Vnira Rakhimovna
  • Tjumkina Tat'Jana Viktorovna
  • Kunakova Rajkhana Valiullovna
  • Ibragimov Askhat Gabdrakhmanovich
RU2447068C1
METHOD OF PRODUCING 2,5-DIALKYL-3-PHENYL(BENZYL)-1,3,4-THIADIAZOLIDINES 2010
  • Dzhemilev Usein Memetovich
  • Murzakova Natalija Nail'Evna
  • Khabibullina Guzel' Razhapovna
  • Akhmetova Vnira Rakhimovna
  • Tjumkina Tat'Jana Viktorovna
  • Kunakova Rajkhana Valiullovna
  • Ibragimov Askhat Gabdrakhmanovich
RU2455294C2
METHOD OF OBTAINING 5-(n-ETHYLCARBOXYPHENYL)-, 5-(n-β-DIETHYLAMINOETHYLCARBOXYPHENYL)- AND 5-(n-SULPHACETAMIDEPHENYL)-1,3,5-DITHIAZINANES 2007
  • Akhmetova Vnira Rakhimovna
  • Nadyrgulova Guzel' Razhapovna
  • Niatshina Zalifa Timerjanovna
  • Kunakova Rajkhana Valiullovna
  • Dzhemilev Usein Memetovich
RU2368603C2
METHOD FOR PREPARING 5-[ORTHO-(PARA)-HYDROXYPHENYL]-1,3,5-DITHIAZINES 2005
  • Dzhemilev Usein Memetovich
  • Akhmetova Vnira Rakhimovna
  • Nadyrgulova Guzel' Razhapovna
  • Khafizova Svetlana Rinatovna
  • Kunakova Rajkhana Valiullovna
  • Tjumkina Tat'Jana Viktorovna
RU2291865C1
METHOD OF PRODUCING BIS-2,4-DIALKYL-1,5,3-DITHIAZEPAN-3-YLS 2010
  • Dzhemilev Usein Memetovich
  • Murzakova Natalija Nail'Evna
  • Khabibullina Guzel' Razhapovna
  • Akhmetova Vnira Rakhimovna
  • Tjumkina Tat'Jana Viktorovna
  • Kunakova Rajkhana Valiullovna
  • Ibragimov Askhat Gabdrakhmanovich
RU2455303C2
METHOD FOR PREPARING (1,5,3-DITIAZEPINAN-3-YL)(THIO)PHENOLS 2011
  • Dzhemilev Usein Memetovich
  • Rakhimova Elena Borisovna
  • Vasil'Eva Inna Vladimirovna
  • Tuljabaev Artur Radisovich
  • Ibragimov Askhat Gabdrakhmanovich
RU2478623C2

RU 2 291 148 C1

Authors

Akhmetova Vnira Rakhimovna

Nadyrgulova Guzel' Razhapovna

Khafizova Svetlana Rinatovna

Kunakova Rajkhana Valiullovna

Tjumkina Tat'Jana Viktorovna

Dzhemilev Usein Memetovich

Dates

2007-01-10Published

2005-07-14Filed