FIELD: medicine, pharmacy.
SUBSTANCE: invention relates to a composition used in solubilization of paclitaxel. The composition comprises the following components, wt.-%: monoolein, 40-89.99 (or 40-64.7 as variants); oil, 10-59.99 (or 25-49.7 as variants), and paclitaxel, 0.3-4 (or 0.01-10 as variants), and to a method for preparing such composition. Paclitaxel-containing compositions don't comprise potentially toxic surface-active substances, show stability for prolonged time and possess high mucoadhesive capacity and high bioavailability.
EFFECT: valuable medicinal and pharmaceutical properties of composition.
22 cl, 5 tbl, 3 dwg, 19 ex
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