FIELD: medicine, laboratory diagnostics.
SUBSTANCE: the present innovation deals with evaluating autoimmunity to ganglioside of human hepatocytes. In blood serum due to immunoenzymatic assay one should detect the content of autoantibodies IgM and IgG to ganglioside of hepatic tissue, calculate the ratio of the content of autoantibodies in tested serum against their content in negative control, and at its value being above 1 it is possible to detect the presence of autoimmune process in human liver. The innovation enables to fulfill diagnostics of autoimmune process in hepatic tissue at higher accuracy and specificity.
EFFECT: increased accuracy and efficiency of evaluation.
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR DIAGNOSIS OF AUTOIMMUNE LIVER INJURY IN PATIENT WITH CHRONIC HEPATITIS | 2003 |
|
RU2247387C1 |
| METHOD FOR DETERMINING CONCENTRATION OF AUTO-ANTIBODIES SPECIFIC TO HUMAN HEPATIC F-PROTEIN IN BIOLOGICAL HUMAN FLUIDS CONTAINING SPECIFIC AUTO-ANTIBODIES | 2003 |
|
RU2236686C1 |
| METHOD FOR EVALUATING HUMORAL ORGAN-SPECIFIC IMMUNITY LEVEL IN THE CASES OF AUTOIMMUNE DISEASES AND STATES | 2002 |
|
RU2213971C1 |
| TEST SYSTEM FOR DETECTING ANTIBODIES TO NUCLEAR PROTEIN OF HEPATITIS C OF IGM CLASS | 1997 |
|
RU2142134C1 |
| METHOD FOR ASSESSING ANTIBODY LEVEL SPECIFIC TO DIFFERENT VARIANTS OF HEPATITIS B VIRUS HBsAg | 2016 |
|
RU2616236C1 |
| METHOD FOR QUANTITATIVE DETECTING CONCENTRATION OF ANTIBODIES SPECIFIC TO ANTIGENS OF HUMAN STEROID-PRODUCING CELLS IN HUMAN BIOLOGICAL LIQUIDS CONTAINING SPECIFIC ANTIBODIES | 2002 |
|
RU2216742C2 |
| METHOD OF DETECTION OF ANTIBODY TO HEPATITIS VIRUS C NUCLEAR PROTEIN | 1997 |
|
RU2133622C1 |
| METHOD OF DETERMINING AVIDITY OF IMMUNOGLOBULIN G TO HERPES VIRUS TYPE 6 | 2015 |
|
RU2596794C1 |
| METHOD FOR EVALUATING ANTIBACTERIAL IMMUNITY TO DIPHTHERIA | 2001 |
|
RU2197730C2 |
| METHOD FOR CARRYING OUT AN ENZYME-LINKED IMMUNOSORBENT ASSAY FOR THE DETECTION OF ANTIBODIES IN A HUMAN BIOLOGICAL SAMPLE SPECIFIC TO THE SARS-COV2 HUMAN CORONAVIRUS, A TEST SYSTEM | 2021 |
|
RU2759149C1 |
