METHOD FOR PREDICTING GENETICALLY DETERMINISTIC HUMAN DISEASES Russian patent published in 2007 - IPC G01N33/53 G01N33/573 

Abstract RU 2293991 C1

FIELD: medicine.

SUBSTANCE: method involves determining patient acetylation phenotype and predicting disease from table data built in advance. The table has morbidity coefficients for predicting diseases under prognosis and mortality rates caused by the diseases in groups of countries where rapid acetylators are predominant in more than 50% of population and in countries where slow acetylators are predominant in more than 50% of population in various age-specific life intervals. Prognosed diseases risks and lethal outcome risks caused by those diseases in given age intervals are determined from the values of the coefficients. The risks are predicted in the cases when said coefficient values corresponding to patient phenotype and sex are greater than the same coefficients of opposite phenotype of the same sex with authenticity level equal to or less than 0.05. Clinical course severity is additionally estimated in said age intervals depending on patient phenotype. Acetylation degree is taken into consideration.

EFFECT: high accuracy of prognosis.

6 cl, 2 tbl

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RU 2 293 991 C1

Authors

Fursenko Sergej Aleksandrovich

Gjul'Azizova Karineh Sergeevna

Nikolaeva Irina Sergeevna

Radkevich Ljudmila Aleksandrovna

Dates

2007-02-20Published

2006-01-24Filed