OPTICALLY ACTIVE DERIVATIVES OF DIHYDROPYRIDINE, THEIR USING AND THERAPEUTIC AGENT BASED ON THEREOF Russian patent published in 2007 - IPC C07D401/12 A61K31/4427 A61P7/10 A61P9/00 A61P9/12 

Abstract RU 2294328 C2

FIELD: organic chemistry, medicine, cardiology.

SUBSTANCE: invention relates to (R)-2-amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridine dicarboxylic acid 3-(1-diphenylmethylazethidin-3-yl) 5-isopropyldiester of the formula (I): or its pharmacologically acceptable salts. Indicated compounds possess antagonistic activity with respect to calcium channels and anti-hypertensive activity and can be used in medicine in treatment of diseases of cardiovascular system.

EFFECT: valuable medicinal properties of compound.

7 cl, 3 tbl, 5 ex

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RU 2 294 328 C2

Authors

Kobajasi Takasi

Sada Tosio

Dates

2007-02-27Published

2003-12-24Filed