PHARMACEUTICAL EMULSION COMPOSITION, METHOD OF ITS PREPARING AND METHOD OF BLOOD PRESSURE DECREASE Russian patent published in 2000 - IPC

Abstract RU 2144358 C1

FIELD: pharmacy. SUBSTANCE: invention proposes pharmaceutical composition as emulsion for intravenous administration. Composition has, wt.%: 1,4-dihydropyridine derivative showing plasma half-life less 30 min, 0.001-20; lipid phase, 1-35; water or buffer, 40-99; and emulsifier in the amount (0.01-2)-fold of lipid phase weight. Invention describes method of preparing emulsions and method of rapid blood pressure decrease by their use in surgery operation and in post-operative period and in the case of impossibility or undesirability of antihypertension oral therapy carrying out. Emulsions provide the rapid release and degradation of dihydropyridine compound at its pharmacological effect as usual solutions. EFFECT: improved properties, diminished adverse effects of carrier, increased stability. 7 cl, 1 tbl, 11 ex

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RU 2 144 358 C1

Authors

Chell' Jal'Mar Andersson

Ehva Kristina Bjured

Anna-Karin Khansson

Margareta Nordlander

Rol'F Krister Vesterlund

Dates

2000-01-20Published

1994-11-03Filed