Show metadata Hide metadata

(19)

(11)

2 365 593

(13)

(51)

IPC

C07D498/04(2006-01-01)

C07D263/00(2006-01-01)

C07D235/00(2006-01-01)

A61K31/41(2006-01-01)

A61P31/00(2006-01-01)

(21) (22)

Application

2006118794/04, 2004-10-29

(24)

Start date

2004-10-29

(22)

Actual filing date

2004-10-29

(45)

Published

2009-08-27

(72)

Inventor

Tsubouti KhidetsuguSasaki KhirofumiItotani MotokhiroKharaguti JosikazuMijamura SinMatsumoto MakotoKhasizume KhirojukiTomisige TatsuoKavasaki MasanoriOkhguro KinueSumida TakumiKhasegava TakesiTanaka KazukhoTakemura Isao

(73)

Holder

Otsuka Farmas'Jutikal Ko., Ltd.

2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOL DERIVATIVES FOR TREATMENT OF TUBERCULOSIS Russian patent published in 2009 - IPC C07D498/04 C07D263/00 C07D235/00 A61K31/41 A61P31/00

Abstract RU 2365593 C2

FIELD: chemistry.

SUBSTANCE: invention relates to derivatives of 2,3-dihydro-6-nitroimidazo[2,1-b]oxazol of general formula (1), as well as to their optically active forms and pharmacologically acceptable salts: where values of R¹, R² and n are given in i.1 of invention formula.

EFFECT: development of compounds, which have bactericidal action against Mycobacterium tuberculosis, polyresistant Mycobacterium tuberculosis and can be applied as antituberculosis medication.

3 cl, 16 ex, 183 tbl, 1515 ex

Similar patents RU2365593C2

Title	Year	Author	Number
METHOD OF OBTAINING 4-NITROIMIDAZOLE COMPOUND	2005	Sinkhama Koiti	RU2345071C2
2,3-DIHYDRO-6-NITROAMIDAZO [2,1-b] OXAZOLE DERIVATIVES	2003	Tsubouti Khidetsugu Sasaki Khirofumi Kuroda Khideaki Itotani Motokhiro Khasegava Takesi Kharaguti Josikazu Kuroda Takesi Matsuzaki Takajuki Tai Kuninori Komatsu Makoto Matsumoto Makoto Khasizume Khirojuke Tomisige Tatsuo Sejke Judzi Kavasaki Masanori Sumida Takumi Mijamura Sin	RU2326121C2
4-PIPERAZIN-1-YL-4-BENZO[b]THIOPHENE DERIVATIVES, SUITABLE FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS	2006	Jamasita Khirosi Kuroda Khideaki Ito Nobuaki Mijamura Sin Osima Kunio Matsubara Dzun Takakhasi Kharuka Fukusima Tae Simizu Satosi Kondo Kazumi Sakuraj Jokhdzi Kuroda Takesi Taira Siniti Itotani Motokhiro Tanaka Tatsuesi	RU2415854C2
ISOXALINE DERIVATIVES AND HERBICIDES COMPRISING THEIR AS ACTIVE COMPONENTS	2000	Nakatani Masao Tamaru Masatosi Kaku Kouitirou Esimura Takumi Kavasaki Khirosi Kobajasi Kazunori Mijazava Takesige	RU2237664C2
DERIVATIVES OF PYRIMIDINYLHYDROXYALKANEAMIDES AND FUNGICIDES FOR AGRICULTURE OR GARDENING	1997	Masuda Katsumi Urusibata Ikumi Asakhara Tsuesi Furuse Katsumi Kodzima Esijuki Muramatsu Norimiti	RU2194040C2
DERIVATIVES OF CARBAMATE AND AGRICULTURE FUNGICIDE	2000	Ozaki Masami Fukumoto Sunitiro Tamai Riudzi Jonekura Norikhisa Ikegaja Kazukhiro Kavasima Takakhiro Sakai Dzunetsu Muramatu Norimiti Takagaki Makikazu Nagajama Kouzou	RU2228328C2
DERIVATIVES OF DOLASTATIN-15	1998	Janssen Bernd Barlotstsari Tereza Khaupt Andreas Tsirke Tomas Kling Andreas	RU2195462C2
2-OXOBUTANOIC ACIDS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF	1997	Muane Zherar Doar Lilian Kergoa Mishelin Mezeraj Filipp Mezanzho Did'E	RU2175966C2
1-SUBSTITUTED 4-NITROIMIDAZOLE DERIVATIVE AND METHOD OF ITS PRODUCTION	2003	Goto Fumitaka Takemura Noriaki Otani Tadaaki Khasegava Takesi Tsubouti Khidetsugu Utsumi Naoto Fudzita Sigekazu Kuroda Khideaki Sitsuta Takuja Sasaki Khirofumi	RU2324682C2
HEAT-SENSITIVE RECORDING MATERIAL CONTAINING NON-PHENOLIC COLOUR DEVELOPERS	2020	Kocak Erkan Bachmann Frank Kulkarni Priti O'Neil Robert Montgomery	RU2824442C1

RU 2 365 593 C2

Authors

Tsubouti Khidetsugu

Sasaki Khirofumi

Itotani Motokhiro

Kharaguti Josikazu

Mijamura Sin

Matsumoto Makoto

Khasizume Khirojuki

Tomisige Tatsuo

Kavasaki Masanori

Okhguro Kinue

Sumida Takumi

Khasegava Takesi

Tanaka Kazukho

Takemura Isao

Dates

2009-08-27—Published

2004-10-29—Filed