METHOD FOR PREPARING 1-DIALKYLAMINO-4-OXOADAMANTANES Russian patent published in 2007 - IPC C07C13/615 C07C209/06 C07C211/38 

Abstract RU 2295513 C1

FIELD: organic chemistry, chemical technology.

SUBSTANCE: invention relates to chemistry of adamantine derivatives, namely to a method for synthesis of 1-dialkylamino-4-oxoadamantanes of the general formula: wherein R means Method involves substitution of bromine atom in 1-bromo-4-oxoadamantane for dialkylamino-group in interaction with dialkylamine chosen from the following order: piperidine, morpholine or piperazine in the mole ratio of reagents = 1:((3-4), at temperature 190-220°C for 7-8 h. Invention provides synthesis of semifinished products used in synthesis of biologically active substances.

EFFECT: improved method of synthesis.

3 ex

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RU 2 295 513 C1

Authors

Popov Jurij Vasil'Evich

Mokhov Vladimir Mikhajlovich

Kkhammo Mishel Veniamin

Dates

2007-03-20Published

2005-12-30Filed