FIELD: organic chemistry, chemical technology.
SUBSTANCE: invention relates to chemistry of adamantine derivatives, namely to a method for synthesis of 1-dialkylamino-4-oxoadamantanes of the general formula: wherein R means Method involves substitution of bromine atom in 1-bromo-4-oxoadamantane for dialkylamino-group in interaction with dialkylamine chosen from the following order: piperidine, morpholine or piperazine in the mole ratio of reagents = 1:((3-4), at temperature 190-220°C for 7-8 h. Invention provides synthesis of semifinished products used in synthesis of biologically active substances.
EFFECT: improved method of synthesis.
3 ex
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Authors
Dates
2007-03-20—Published
2005-12-30—Filed