METHOD FOR PRODUCTION OF 2-AMINO-2-CYANOADAMANTANE OR DERIVATIVES THEREOF Russian patent published in 2007 - IPC C07D295/33 C07C255/58 

Abstract RU 2307123 C1

FIELD: organic chemistry.

SUBSTANCE: invention relates to new method for production of compounds of general formula

R=-NH2, -NHCH2CH2OH, -NHCH2C6H5, -NHNHC6H3(NO2)2, -NHNH2, -NHNHC6H5, -NHCH2СН2NH2.

, , .

Claimed method includes interaction of 2-hydroxy-2-cyanoadamantane with ammonia or derivatives thereof such as piperidine, piperazine, 1,2-diaminoethane, etc, in ethanol medium, at 20-80°C for 8-72 h.

EFFECT: enhanced assortment of adamantine derivatives useful as synthetic intermediates for bioactive compounds, method of increased yield.

1 cl, 10 ex

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RU 2 307 123 C1

Authors

Popov Jurij Vasil'Evich

Mokhov Vladimir Mikhajlovich

Kkhammo Mishel Veniamin

Dates

2007-09-27Published

2006-05-30Filed