METHOD FOR PREDICTING TUBERCULOSIS ETIOLOGY OF CHORIORETINITIS Russian patent published in 2007 - IPC A61B8/10 G01N33/50 

FIELD: medicine, ophthalmology.

SUBSTANCE: one should apply tuberculin samples for testing the picture of an eyeground through fixed time intervals. Ultrasound dopplerography should be used for detecting in central retinal artery (CRA) and posterior short ciliary arteries (PSCA) the values of circulation the alteration of which should be registered twice - before tuberculin samples and in 48 h. Moreover, one should register the alterations of maximal systolic velocity of circulation - Vs, minimal diastolic velocity of circulation - Vd and index of peripheral resistance - Ri; one should investigate initial state of systemic humoral immunity. Then, at the decrease of Vs threshold value by 25% and Ri increase - by 26% in CRA, and, also, Vs and Vd decrease by 35% and Ri increase by 40% in PSCA, moreover, at decreased quantity of CD22 lymphocytes by 26%, Immunoglobulins A and G by 13%, considerable increase of circulating immune complexes (CIC) ranged 64-87%, increased content of complement C3 and C4 components by 57% and 179%, correspondingly, the decrease of total hemolytic complement activity by 30%, increased content of immunoglobulin M ranged 9-27% it is possible to diagnose tuberculosis etiology of chorioretinitis. The innovation enables to state upon tuberculosis etiology of chorioretinitis at minimal manifestation of focal reaction in ocular tissues, it excludes pilot therapy and enables to shorten the terms of etiological diagnostics of tuberculosis chorioretinitis considerably.

EFFECT: higher accuracy and efficiency of diagnostics.

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