ASIA-1-TYPE FOOT-AND-MOUTH DISEASE VIRUS STRAIN FOR PRODUCING OF DIAGNOSTIC AND/OR VACCINE PREPARATIONS Russian patent published in 2007 - IPC C12N7/00 A61K39/135 C12R1/93 

Abstract RU 2297452 C2

FIELD: biotechnology, virology.

SUBSTANCE: claimed strain is obtained by passaging of epizootic isolate on sensitive hetero- and homologous cell cultures. Virus strain is reproduced in sensitive cell cultures and after incubation for 18-24 h 6.0-7.66 lg TCD50/ml is accumulated. In case of mass infection strain takes cytopathic effect over 5 hours, and retains starting characteristics for 10 passages.

EFFECT: strain of high biological, antigenic and immunogenic activity.

1 dwg, 7 tbl, 5 ex

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RU 2 297 452 C2

Authors

Zakharov Valerij Mikhajlovich

Gruzdev Konstantin Nikolaevich

Fomina Tamara Alekseevna

Spirin Vladimir Kuz'Mich

Shcherbakov Aleksej Vladimirovich

Muminov Dzhurabek Moseevich

Mikhalishin Dmitrij Valer'Evich

Lezova Tat'Jana Nikolaevna

Musiev Dzhabrail Gabibulaevich

Dates

2007-04-20Published

2005-06-07Filed