FIELD: veterinary virology, biotechnology. SUBSTANCE: new strain of foot-and-mouth virus of type Asia-1 = 1737/Georgia/2000-DEP is obtained by multiple sequential passages on sensitive hetero- and homologous cell cultures. The strain is reproduced in sensitive cell cultures and for 22-24 h of incubation the accumulation of cells is up to 7.2-8.2 lgTЦД50/ml. In massive infection the strain causes cytopathologic action in 4 h. The strain retains the parent indices in passage in cell cultures for 10 passages. The obtained strain shows high biological, antigenic and immunogenic activity. The strain can be used for preparing agents for specific prophylaxis and diagnosis of foot-and-mouth of type Asia-1 that shows homology with virus circulating in countries of the Transcaucasus, Central Asia and Near East. EFFECT: valuable properties of strain. 2 dwg, 14 tbl, 9 ex
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Authors
Dates
2003-12-10—Published
2002-07-10—Filed