FOOT-AND-MOUTH VIRUS STRAIN "PRIMORSKY-2000" 1734 OF TYPE O FOR DIAGNOSTIC AND VACCINE PREPARATION PREPARING Russian patent published in 2003 - IPC

Abstract RU 2204599 C1

FIELD: veterinary virology, biotechnology. SUBSTANCE: the strain "Primorsky-2000" 1734 is obtained by multiple successive passages in sensitive cell cultures. The strain is deposited in the Collection of microorganisms VGNKI 22.03.2000 at registration 1734 "Primorsky-2000-DEP". Virus of the strain O1 1734 "Primorsy-2000" is reproduced in sensitive cell cultures for 20-24 h of incubation and accumulates in the amount up to 7.5-8.0 lg TCO50/ml. In total infection the strain causes ЦПД in 4 h and retains parent indices in passage in cell cultures for 10 passages. Foot-and-mouth virus strain O1 shows high biological, antigenic and immunogenic activity and useful for preparing agent for specific prophylaxis and diagnosis of foot-and-mouth virus of type O1 showing homology to epizootic virus distributing in Russia, regions of Asia continent including South-East and Middle Asia. EFFECT: valuable properties of strain. 12 tbl, 2 dwg, 5 ex

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Authors

Zakharov V.M.

Fomina T.A.

Spirin V.K.

Gusev A.A.

Kruglikov B.A.

Kamalova N.E.

Mikhalishin D.V.

Karaulov A.K.

Andreev V.G.

Shcherbakov A.V.

Dates

2003-05-20Published

2001-11-01Filed