METHOD FOR ENDOVASCULAR TREATMENT OF ALZHEIMER'S DISEASE Russian patent published in 2007 - IPC A61N5/67 A61M25/01 

FIELD: medicine.

SUBSTANCE: according to a certain technique one should puncture and catheterize a total femoral artery along with applying an introducer of 6-9 F diameter. Through this introducer one should coaxially apply and install the first conductor catheter of 5-8 F diameter and modeled distal part in the trunk of the inner carotid artery; through it is necessary to coaxially apply the second modeled conductor catheter of 4-5 F diameter to be superselectively installed in median cerebral and anterior cerebral arteries. Successively, through it one should coaxially apply a flexible roentgenocontrast catheter of 2-3.5 F diameter with a movably located flexible quartz-quartz or quartz-polymeric light guide at diameter of light-conducting fiber ranged 50-100 mcm and total diameter of about 300-400 mcm. The light guide should be moved along the vessel towards the site of microcirculatory vascular tract lesion in distal departments. The first conductor catheter should be descended and applied in descending part of aortic arch, the second one should be descended and applied in proximal part of total carotid artery. Then it is necessary to affect with low-energy laser, the power being 20 mW, the mode should be either uninterrupted, or impulse, or combined. During irradiation it is important to introduce heparinized physiological solution at 0.1 U heparin/ml physiological solution, the rate of injection corresponds to 0.1 ml/sec, not less. The innovation enables to reconstruct microcirculatory vascular tract in brain along with regeneration of surrounding cerebral tissues.

EFFECT: higher efficiency of therapy.

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