FIELD: medicine.
SUBSTANCE: method involves determining interleukine-10 content in daily urine by applying immunoenzyme assay. Transforming growth factor β1 content is additionally determined. Prosclerotic coefficient value is calculated as transforming growth factor β1 and interleukine-10 ratio. The value being less than 0.95, moderate compensated nephrosclerosis is to be diagnosed. The value being greater than 3.0, marked irreversible nephrosclerosis is to be diagnosed.
EFFECT: high accuracy of early stage diagnosis.
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