FIELD: medicine, neurology.
SUBSTANCE: the present innovation deals with predicting the development of syringomyelia one should isolate DNA out of peripheral venous blood lymphocytes due to the technique of phenol-chloroform extraction. It is necessary to carry out genotyping A/MspI polymorphism linked with gene alpha 1 of collagen chain type I (Col1A1) and B/MspI polymorphism in gene alpha II of collagen chain type I (Col1A2). At detecting genotype A/MspI*A/*A and/or B/MspI*N/*N one should predict the risk in the development of syringomyelia in a patient under testing. The present innovation enables to increase accuracy and objectivity in predicting the development of syringomyelia.
EFFECT: higher efficiency of prediction.
2 dwg, 1 ex, 2 tbl
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Authors
Dates
2007-08-20—Published
2006-10-27—Filed