FIELD: medicine; gynecology.
SUBSTANCE: invention can be used to predict the risk of genital prolapse in pre-clinical parous women. Obstetric-gynecological history is collected—presence or absence of abnormal uterine bleeding during life, endometrial polyp, three spontaneous abortions, birth of a large fetus; perineal height measurement in millimeters. Molecular genetic analysis of energy exchange gene polymorphism is performed PPARGC1A Gly482Ser, PPARD A/G rs2016520 and vitamin D receptor gene VDR Met1Thr. Results are evaluated in points, which are substituted into the formula for calculating the prognostic index PI. If PI≥0, a high risk of genital prolapse is predicted. If PI <0, a low risk of genital prolapse is predicted.
EFFECT: method provides higher information value and reliability of predicting the risk of genital prolapse by using the original formula for calculating the prognostic index PI.
1 cl, 1 dwg, 6 tbl, 2 ex
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