FIELD: medicine.
SUBSTANCE: DNA is recovered from patient's peripheral venous blood lymphocytes. That is followed by genetic typing of polymorphic versions of rs7216389 gasdermin B (GSDMB) gene, rsl2342831 beta 1,4-galactosyl trabsferase 1 (B4GALT1) gene and rsl496499 binding insulin-like growth factor protein 3 (IGFBP3) gene. If observing one of the combinations of genotypes by three polymorphous loci of the genes; GSDMB*rs7216389C/T B4GALTl*rsl2342831T/T - lGFBP3*rsl496499T/G; GSDMB*rs7216389T/T -B4GALTl*rsl2342831T/T - IGFBP3*rsl496499T/G\ GSDMB*rs72J6389T/T -B4GALT1*rsl234283 JT/T - IGFBP3*rsl496499T/T, a risk of developing bronchial asthma in individuals of various ethnicities is predicted.
EFFECT: effective method for prediction the risk of developing bronchial asthma and promotes the working out of preventive measures considering the patient's traits.
1 tbl, 2 ex
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Authors
Dates
2014-03-27—Published
2012-07-13—Filed