FIELD: biotechnology, gene engineering, medical microbiology.
SUBSTANCE: invention relates to recombinant pHP61 plasmid expressing cloned hapA gene Vibrio cholerae hemagglutinin/protease and E.coli strain bearing recombinant pHP61 plasmid as producer of vibrio cholerae hemagglutinin/protease (HA/P).
EFFECT: production of hemagglutinin/protease without using of hazardous disease exciters; HA/P of high purity.
2 cl, 2 dwg, 4 ex
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