COMPOSITION WITH LONG-LASTING BIOCIDAL EFFECT AND THE COMPOSITION MOUTHWASH Russian patent published in 2023 - IPC A61K8/19 A61K8/27 A61K8/29 A61K8/365 A61Q11/00 

FIELD: antibacterial agents.

SUBSTANCE: inventions group relates to antibacterial agents field. A composition with long-lasting biocidal effect is a colloidal solution that consists of a disperse phase mixed with a stabilizer and a solvent in the form of distilled water with a mass concentration of 99.991-99.99991%, where the disperse phase includes silver, gold, platinum, copper, copper oxide (I), copper oxide (II), zinc oxide, double iron oxide Fe₃O₄, titanium dioxide, tantalum dioxide or tantalum pentoxide particles in a mass concentration of 8⋅10^-3 to 7.9⋅10^-5% and in size of 0.5 to 10 nm taken separately or in combination. A citric acid or sodium citric acid, or potassium citric acid, or a combination thereof, at a mass concentration of 1⋅10^-3-1.1⋅10^-5% is a stabilizing additive. The metal or metal oxide particles are obtained via condensation of a low temperature plasma consisting of metal, oxygen and hydrogen atoms in distilled water at a temperature between 0°C and 50°C. A mouthwash based on the composition is also proposed, it is a colloidal solution of mixed dispersed phase, stabilizing additive and solvent in the form of distilled water with a mass concentration of 99.99991-99.9999991%, the disperse phase includes the above particles with size of 0.5 nm to 10 nm with mass concentration of 8⋅10^-5-8⋅10^-7% and the stabilizing additive mass concentration is 1·10^-5-1⋅10^-7%. The final concentration of the metal nanoparticles dispersed phase and/or metal oxides in the mouthwash based on the concentrate (composition) provides a guaranteed sanitary and environmental safety of use with a high level of antibacterial properties against dental plaque microflora.

EFFECT: invention increases oral hygienic hygiene by using a dispersed phase of metal nanoparticles or metal oxides not exceeding 10 nm in size as a biocidal component in the solution.

2 cl, 4 tbl