FIELD: medicine.
SUBSTANCE: method involves carrying out Doppler ultrasonographic examination of eye and orbit blood vessels and determining glycolysis intensity and direction and cell membrane lipid peroxidation activity in lacrimal fluid and blood serum. Numeric index is calculated for each of the following factor groups. They are local hypoxia, blood circulation in posterior long ciliary arteries, blood circulation in orbital artery, blood supply of retinal periphery, blood circulation in orbital artery and in posterior short ciliary arteries, lipid peroxidation start, central retinal artery resistance, systemic hypoxia and dystrophy process markers. The calculated index values are compared to corresponding reference values for each clinical disease course type. Low blood circulation value being found in the orbital artery and central retinal artery, anaerobic glycolysis and lipid peroxidation indices being high, stable clinical dystrophy process course is to be diagnosed. Non-penetrating defects, penetrating retina ruptures being detected, fresh dystrophy foci being available/found, increased blood circulation speed in orbital artery and central retinal artery being the case and lipid peroxidation being activated with product concentrations growing 3-4 times as high, progressive clinical dystrophy process course is to be diagnosed. Doppler ultrasonographic examination parameters falling on the background of rising lipid peroxidation intensity and rising anaerobic glycolysis parameters intensity, complicated clinical dystrophy process course is to be diagnosed.
EFFECT: enhanced effectiveness of diagnosis procedures.
3 dwg, 2 tbl
Authors
Dates
2007-10-20—Published
2006-01-10—Filed