METHOD FOR TREATING FALSE ARTICULATIONS DUE TO TRANSPLANTATION OF AUTOLOGOUS MESENCHYMAL STEM CELLS AND BIOTRANSPLANT FOR ITS APPLICATION Russian patent published in 2007 - IPC A61K35/28 A61B17/56 

Abstract RU 2309756 C1

FIELD: medicine, traumatology, orthopedics.

SUBSTANCE: it is necessary to carry out the resection of false articulation, form surgically a groove through distal and proximal fragments for the whole thickness of cortical layer to fill in this developed groove with biotransplant that contains viable autologous CD 44+; CD 90+; CD 105+; CD 106+; CD 45-; CD 34-mesenchymal stem cells being homogeneous by phenotype, isolated out of bone marrow, inoculated onto the matrix obtained out of demineralized bony allotransplant. One should conduct fixation and stabilization of bony fragments. The group of innovations enables to accelerate osteogenesis and angiogenesis and reconstruct bone structure in the site of lesion.

EFFECT: higher efficiency of therapy.

7 cl, 57 dwg, 3 ex

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RU 2 309 756 C1

Authors

Shchepkina Elena Andreevna

Krugljakov Petr Vladimirovich

Solomin Leonid Nikolaevich

Polyntsev Dmitrij Genrikhovich

Zaritskij Andrej Jur'Evich

Nazarov Vladimir Anatol'Evich

Vijde Svetlana Konstantinovna

Shvedova Evgenija Viktorovna

Dates

2007-11-10Published

2006-07-03Filed