FIELD: pharmaceutical industry.
SUBSTANCE: invention relates to application of 2-hydroxyoleic acid and analogs thereof in production of drugs useful in diseases associated with G-proteins and mediated by membrane structure transition from lamellar structure to hexagonal one. Discribed is application of compounds of general formula I: COOH-CHR-(CH2)m-CH=-CH-(CH2)n-CH3, wherein R represents OH or NH2; m and n = 1-6 in production of drugs useful in treatment of cancer; as well as compounds of formula I, wherein R represents H, OH, NH2 or CH3, useful in treatment of hypertension and obesity.
EFFECT: drugs with increased effectiveness.
8 cl, 11 dwg, 3 tbl, 11 ex
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Authors
Dates
2007-11-20—Published
2002-10-09—Filed