FIELD: organic chemistry, medicine, pharmacology, pharmacy.
SUBSTANCE: invention relates to an antibacterial composition representing a complex of polyvinylpyrrolidone and metronidazol of the formula (I) wherein n = 76-276; m = 5-40, and containing 9-19% of metronidazol. Also, the invention relates to a method for preparing the indicated complex. The proposed composition provides maintaining the concentration of metronidazol at the therapeutic level for 48 h.
EFFECT: improved and valuable medicinal and pharmaceutical properties of composition.
3 cl, 5 tbl, 5 ex
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Authors
Dates
2007-11-20—Published
2005-06-14—Filed