ANTIBACTERIAL PHARMACEUTICAL COMPOSITION POSSESSING PROLONGED EFFECT Russian patent published in 2007 - IPC A61K31/4164 A61K31/4178 C08F126/10 A61P31/04 

Abstract RU 2310448 C2

FIELD: organic chemistry, medicine, pharmacology, pharmacy.

SUBSTANCE: invention relates to an antibacterial composition representing a complex of polyvinylpyrrolidone and metronidazol of the formula (I) wherein n = 76-276; m = 5-40, and containing 9-19% of metronidazol. Also, the invention relates to a method for preparing the indicated complex. The proposed composition provides maintaining the concentration of metronidazol at the therapeutic level for 48 h.

EFFECT: improved and valuable medicinal and pharmaceutical properties of composition.

3 cl, 5 tbl, 5 ex

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RU 2 310 448 C2

Authors

Antonik Lidija Makarovna

Khabibulina Al'Fija Galimullovna

Lopyrev Vladimir Aleksandrovich

Fadeeva Tat'Jana Vladimirovna

Kuznetsova Ehmma Ehfroimovna

Grigor'Ev Evgenij Georgievich

Kogan Aleksandr Semenovich

Dates

2007-11-20Published

2005-06-14Filed