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2 532 328

(13)

(51)

IPC

A61K31/198(2006-01-01)

A61K33/38(2006-01-01)

A61P31/04(2006-01-01)

(21) (22)

Application

2013147358/15, 2013-10-23

(24)

Start date

2013-10-23

(22)

Actual filing date

2013-10-23

(45)

Published

2014-11-10

(72)

Inventor

Sil'Nikov Vladimir NikolaevichBurakova Ekaterina Anatol'EvnaKoroleva Ljudmila SergeevnaJarinich Ljubov' Aleksandrovna

(73)

Holder

Federal'Noe Gosudarstvennoe Bjudzhetnoe Uchrezhdenie Nauki Institut Khimicheskoj Biologii I Fundamental'Noj Meditsiny Sibirskogo Otdelenija Rossijskoj Akademii Nauk So Ran)

AGENT POSSESSING ANTIBACTERIAL ACTIVITY Russian patent published in 2014 - IPC A61K31/198 A61K33/38 A61P31/04

Abstract RU 2532328 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medicine, namely to broad-spectrum antibacterial preparations. What is presented is an agent representing sodium dihydroxocystine diaminodiargenate possessing the antibacterial activity. The agent represents a complex C₆H₁₂Ag₂N₂Na₂O₆S₂ of two silver ions with a disodium salt of natural amino acid L-cystine being coordinately linked. The method for preparing the agent involves adding an estimated amount of argentous oxide to a solution of cysteine disodium salt, mixing a reaction mixture at room temperature until argentous oxide dissolves completely, and precipitating a target product in alcohol.

EFFECT: new agent, sodium dihydroxocystine diaminodiargenate possesses the evident antibacterial action on the pathogenic strains of Staphylococcus, Proteus, Salmonella typhimurium, Pseudomonas aeruginosa, and also inhibits the yeast growth, has low toxicity and storage-stability.

1 tbl, 4 ex

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RU 2 532 328 C1

Authors

Sil'Nikov Vladimir Nikolaevich

Burakova Ekaterina Anatol'Evna

Koroleva Ljudmila Sergeevna

Jarinich Ljubov' Aleksandrovna

Dates

2014-11-10—Published

2013-10-23—Filed